Long‐term survival after heart transplantation for cardiac sarcoidosis

Background Cardiac sarcoidosis is an increasingly common indication for a heart transplant, but there paucity of knowledge with regard to long-term outcomes following transplant. Methods We utilized the Organ Procurement and Transplantation Network database retrospectively analyze adult patients undergoing first-time, single-organ transplant between January 1999 March 2020. Results Of 41,447 that underwent during study period, 289 (0.7%) were transplanted primary diagnosis restrictive cardiomyopathy due cardiac (RCM-Sarcoidosis). RCM-Sarcoidosis was associated 33% reduced risk mortality over 10 years compared non-RCM indications in multivariable Cox proportional hazards model (p = .03). Ten-year survival functions improved among this reference group (73.4% [64.2%–80.6%] vs. 59.5% [58.8%–60.1%], p .002). Among after who had at least follow-up (n 19,489), median 11.9 [8.3–14.6] while 9.9 [4.0–13.1] years. not increased secondary such as graft failure, rejection, or infection. The incidence retransplant comparable (1.38% 1.50%, .93). Conclusions These data suggest are favorable other indications.